Heavy metals, kidney stress and coriander (also known as cilantro)

Some very interesting research links

CADMIUM AND ITS EFFECTS ON THE KIDNEY
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615899/

CORIANDER LEAF HELPS TO HEAL THE KIDNEYS
Nishio R, Tamano H, Morioka H, Takeuchi A, Takeda A. Intake of Heated Leaf Extract of Coriandrum sativum Contributes to Resistance to Oxidative Stress via Decreases in Heavy Metal Concentrations in the Kidney. Plant Foods Hum Nutr. 2019 Jun;74(2):204-209. doi: 10.1007/s11130-019-00720-2. PMID: 30783906.
Coriandrum sativum (coriander) is an annual herb of the Apiaceae family and has been used as a traditional remedy. Here we examined whether heated leaf extract of coriander decreases the concentrations of heavy metals in tissues. Male ddY mice were given a drinking water containing 0.25% of heated leaf extract of coriander for 8 weeks. Eight weeks after the intake, the concentrations of zinc, iron, copper, arsenic, and cadmium were measured in the liver and kidney. The intake of coriander did not modify the concentrations of all heavy metals tested in the liver, but decreased the concentrations of iron, arsenic, and cadmium in the kidney. Because heavy metals can induce oxidative stress, the effect of coriander intake on hydrogen peroxide-induced oxidative stress was compared between slices from the kidney and liver. The slices were immersed in Ringer solution containing 100 μM hydrogen peroxide and aminophenyl fluorescein (APF), a probe for detecting reactive oxygen species (ROS). APF fluorescence was markedly increased in the control kidney slices, while the increase was completely blocked in kidney slices from coriander intake group. In contrast, APF fluorescence was also markedly increased in the control liver slices, while the increase was not blocked by coriander intake. The present study indicates that intake of coriander leaf extract contributes to powerful resistance to oxidative stress in the kidney, probably via decreased concentrations in heavy metals. It is likely that decrease in arsenic concentration to the detection limit is a major factor for the resistance.
https://pubmed.ncbi.nlm.nih.gov/30783906/

PHYTONUTRIENTS PROTECTION AGAINST POLLUTANTS
Chung RT. Detoxification effects of phytonutrients against environmental toxicants and sharing of clinical experience on practical applications. Environ Sci Pollut Res Int. 2017 Apr;24(10):8946-8956. doi: 10.1007/s11356-015-5263-3. Epub 2015 Aug 28. PMID: 26310706.
https://pubmed.ncbi.nlm.nih.gov/26310706/

CORIANDER PROTECTION AGAINST LEAD TOXICITY
Sharma V, Kansal L, Sharma A. Prophylactic efficacy of Coriandrum sativum (Coriander) on testis of lead-exposed mice. Biol Trace Elem Res. 2010 Sep;136(3):337-54. doi: 10.1007/s12011-009-8553-0. Epub 2009 Nov 10. PMID: 19902160.
https://pubmed.ncbi.nlm.nih.gov/19902160/

EXTRAORDINARY: MERCURY FOUND TO INHIBIT THE ABILITY OF ANTIBIOTICS TO TREAT CERTAIN INFECTIONS. THE ADDITION OF CORIANDER LEAF TREATMENT HELPS TO IMPROVE ANTIBIOTIC EFFICACY
Omura Y, Beckman SL. Role of mercury (Hg) in resistant infections & effective treatment of Chlamydia trachomatis and Herpes family viral infections (and potential treatment for cancer) by removing localized Hg deposits with Chinese parsley and delivering effective antibiotics using various drug uptake enhancement methods. Acupunct Electrother Res. 1995 Aug-Dec;20(3-4):195-229. doi: 10.3727/036012995816357014. PMID: 8686573.
https://pubmed.ncbi.nlm.nih.gov/8686573/